Chosen Solution

I can get the touch screen to respond perfectly and then when I close the screen back up it stops working! HELP!

You will need to inspect the work you have done. Follow this guide. Also follow this guide if you moved the Front Camera & Sensor Flex from the original screen to your replacement screen. Look for improperly seated Front & Rear Camera or the screen retaining bracket. Be careful with the screws; put them back where their supposed to go or you will cause additional damage. Also disconnect the battery first and connect it last.