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hello i have a desktop hp pavilion slimline my usb ports are not working , it doesnt detect the mouse or keyboard what can i do to use my pc again.

First make sure the proper drivers for USB are installed and not corrupted If they are you have three choices–1. Replace the motherboard (expensive) 2. Install a USB IO card in one of your io slots.(about $20 + shipping) 3. Use USB to PS2 adapters to connect your keyboard and mouse to the computer.